. 2019 Apr 8;97(6):2342–2356. doi: 10.1093/jas/skz110

Table 5.

Villous height, crypt depth, villous height: crypt depth ratio, histologic score and diarrhea rate [mean (SD)] of the intestine in Exp. 2

Item	Treatment group¹
	CON-2	K88	K88 + APK
Duodenum
Villous height, µm	496 (22)^a	277 (18)^b	416 (30)^c
Crypt depth, µm	231 (25)	286 (8)	293 (26)
Villous height:crypt depth ratio	2.31 (0.32)^a	0.97 (0.06)^b	1.44 (0.10)^b
Jejunum
Villous height, µm	461 (37)^a	289 (12)^b	427 (23)^a
Crypt depth, µm	204 (15)^a	280 (6)^b	210 (18)^a
Villous height:crypt depth ratio	2.30 (0.22)^a	1.03 (0.04)^b	2.03 (0.11)^a
Ileum
Villous height, µm	378 (31)^a	265 (15)^b	353 (30)^a
Crypt depth, µm	172 (16)^a	269 (9)^b	237 (23)^b
Villous height: crypt depth ratio	2.30 (0.27)^a	0.99 (0.09)^b	1.56 (0.19)^b
Histologic score	0.22 (0.32)^a	3.50 (0.65)^b	0.97 (0.21)^c
Diarrhea rate (day 4 to day 6), %	0 (0)^a	88.9 (17.2)^b	66.6 (29.9)^b

^a–cMeans within a row with different superscripts differ (P < 0.05).

¹CON-2 = piglets with an oral administration of fresh Luria–Bertani broth (50 mL) followed by an intraperitoneal (i.p.) injection of an equivalent volume of PBS; K88 = piglets orally challenged with 1 × 10¹⁰ cfu ETEC K88 on day 1 followed by an i.p. injection of an equivalent volume (1 mL) of PBS; K88 + APK = piglets orally challenged with 1 × 10¹⁰ cfu ETEC K88 on day 1 followed by an i.p. injection of 0.6 mg/kg KR-32. n = 6 for the CON-2 group, n = 5 for the K88 group, and n = 5 for the K88 + APK group.