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. 2019 May 17;23:e00344. doi: 10.1016/j.btre.2019.e00344

Table 1.

Experimental range of variables for the central composite rotatable design (CCRD)

Variable Symbol coded Range of variables (g/l)
Low
(-1)		 Mid
(0)		 High
(+1)
pH A 2.75 5.5 11
Glucose B 8.5 17 34
Yeast extract C 0.65 1.3 2.6
KH2PO4 D 0.4 0.8 1.6
CuSO4 E 1 mM 2 mM 4 mM