Table 1.
Demographic and anamnestic characteristics of patients included in the study.
| Parameters | Total cohort (n=1003) | AF-HFpEF (n=387) | AF-HFmEF (n=150) | AF-HFrEF (n=466) | p level |
|---|---|---|---|---|---|
| Demography and habits | |||||
| Age, years | 68 (60 : 76) | 72 (63 : 78) | 67 (58 : 75) | 66 (58 : 75) | <0.001 |
| The proportion of patients ≥65 years of age | 589 (58.7%) | 270 (69.8%) | 82 (54.7%) | 237 (50.9%) | <0.001 |
| The proportion of patients ≥75 years of age | 310 (30.9%) | 157 (40.6%) | 38 (25.3%) | 115 (24.7%) | <0.001 |
| Female sex, n (%) | 437 (43.6%) | 253 (65.4%) | 64 (42.7%) | 120 (25.8%) | <0.001 |
| Body mass index ≥30 | 360 (35.9%) | 147 (38%) | 62 (41.3%) | 151 (32.4%) | 0.076 |
| Low level of physical activity (exercise less than 30 min/day, no more than 3 times/week) | 570 (56.8%) | 191 (49.4%) | 96 (64%) | 283 (60.7%) | <0.001 |
| Smoking | |||||
| Never | 603 (60.1%) | 295 (76.2%) | 84 (56%) | 224 (48.1%) | <0.001 |
| Quit smoking | 216 (21.5%) | 53 (13.7%) | 38 (25.3%) | 125 (26.8%) | |
| Active smoker | 184 (18.3%) | 39 (10.1%) | 28 (18.7%) | 117 (25.1%) | |
| Comorbidities and pathologies | |||||
| Hypertension, fact | 653 (65.1%) | 263 (68%) | 108 (72%) | 282 (60.5%) | 0.012 |
| Hypertension, duration, years | 14 (10 : 20) | 13 (10 : 20) | 10 (7.5 : 20) | 15 (10 : 20) | 0.916 |
| Ischemic heart disease | 686 (68.4%) | 271 (70%) | 107 (71.3%) | 308 (66.1%) | 0.336 |
| Diabetes mellitus | 247 (24.6%) | 89 (23%) | 38 (25.3%) | 120 (25.8%) | 0.632 |
| Previous stroke/TIA | 158 (15.8%) | 58 (15%) | 22 (14.7%) | 78 (16.7%) | 0.747 |
| Previous myocardial infarct | 382 (38.1%) | 98 (25.3%) | 61 (40.7%) | 223 (47.9%) | <0.001 |
| Vascular disease | 502 (50%) | 157 (40.6%) | 74 (49.3%) | 271 (58.2%) | <0.001 |
| Abnormal renal function | 145 (14.5%) | 45 (11.6%) | 24 (16%) | 76 (16.3%) | 0.123 |
| Abnormal liver function | 101 (10.1%) | 12 (3.1%) | 20 (13.3%) | 69 (14.8%) | <0.001 |
| Family history | |||||
| Family history of coronary artery disease early development | 230 (22.9%) | 78 (20.2%) | 43 (28.7%) | 109 (23.4%) | 0.106 |
| Hypertension in relatives | 516 (51.4%) | 231 (59.7%) | 84 (56%) | 201 (43.1%) | <0.001 |