Table 5.
Main outcomes in AF-CHF subgroups.
| Endpoints | Total cohort (n=1003) | AF-HFpEF (n=387) | AF-HFmrEF EF (n=150) | AF-HFrEF (n=466) | p level |
|---|---|---|---|---|---|
| Hospitalization for worsening of heart failure | 574 (57.2%) | 204 (52.7%) | 99 (66%) | 271 (58.2%) | 0.017 |
| Cardiovascular mortality | 102 (10.2%) | 16 (4.1%) | 14 (9.3%) | 72 (15.5%) | <0.001 |
| Thromboembolic events | 34 (3.4%) | 14 (3.6%) | 7 (4.7%) | 13 (2.8%) | 0.451 |
| Ischemic stroke | 27 (2.7%) | 12 (3.1%) | 4 (2.7%) | 11 (2.4%) | 0.776 |
| Myocardial infarct | 101 (10.1%) | 26 (6.7%) | 20 (13.3%) | 55 (11.8%) | 0.014 |
| Combined point (stroke, IM, and CV death) | 201 (17%) | 49 (12.7%) | 33 (22%) | 119 (25.5%) | <0.001 |
| Bleeding rate | 39 (3.9%) | 15 (3.9%) | 7 (4.7%) | 17 (3.6%) | 0.815 |