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. 2019 May 16;2019:7329131. doi: 10.1155/2019/7329131

Figure 4.

Figure 4

ERS induction compromised and ERS prevention amplified the protective effects of Mdivi-1 on CD4+ T cells after LPS treatment. Activated CD4+ T cells were copretreated with Mdivi-1 (20 μM) and tunicamycin (1.6 μg/mL) or 4-PBA (2 mmol/L) before LPS stimulation. (a) Representative photomicrographs of CD4+ T cells (around 20 cells) after colabeling TUNEL/DAPI and around 400 cells in each group evaluated to determine the percentage of TUNEL-positive cells. (b) Viability analysis of CD4+ T cells. Scale bars, 50 μm. The results are shown as the mean ± SD; n = 5. ∗ P < 0.05 vs. the control group (∗∗ P < 0.01, ∗∗∗ P < 0.001); & P < 0.05 vs. the LPS group (&& P < 0.01, &&& P < 0.001); ## P < 0.01 vs. the LPS+Mdivi-1 group.