Table 2.

Median time to treatment failure on treatment regimen received immediately after TREnd, according to the absolute number of previous lines of treatment received. This takes into account previous endocrine therapy line(s) +/− chemotherapy (TREnd allowed subjects to have a maximum of one previous line of chemotherapy for advanced disease prior to enrolment)

Number of previous lines of treatment received	Patients (number)	Recorded events (number)	Median TTF (months)	95% CI
Two lines	51	47	3.73	3.39–5.07
Three lines	44	43	4.18	3.09–6.28
Four lines	10	9	3.85	2.20–NA

TTF time to treatment failure, CI confidence interval, NA not assessable