Table 1.
Results of the additive, dominant and recessive TTT models. Polymorphisms with a BH-adjusted P-value < 0.1 are show
| rs ID | P-value | BH-adjusted P-value | Reference | Alternative | Gene Symbol | Hazard Ratio | MAF |
|---|---|---|---|---|---|---|---|
| ADDTIVE MODEL | |||||||
| rs537453728 | 4.53E-08 | 5.39 E-3 | CT | C | MAP3K4 | 7.08 | 0.01 |
| rs361807 | 4.31E-07 | 0.01 | T | C | PEX26 | 4.55 | 0.1 |
| rs361946 | 4.31E-07 | 0.01 | A | G | PEX26 | 4.55 | 0.1 |
| rs1043278 | 4.31E-07 | 0.01 | A | G | PEX26 | 4.55 | 0.1 |
| rs7620924 | 5.08E-07 | 0.01 | A | G | PPP4R2 | 0.24 | 0.49 |
| rs5992169 | 9.55E-07 | 0.02 | G | A | PEX26 | 4.45 | 0.11 |
| rs9463 | 3.11E-06 | 0.05 | G | A | TTLL12 | 3.18 | 0.42 |
| rs55715863 | 3.84E-06 | 0.05 | C | A | TXNRD2 | 5.24 | 0.01 |
| rs3780333 | 3.84E-06 | 0.05 | A | G | ZCCHC7 | 4.8 | 0.27 |
| rs17016977 | 5.69E-06 | 0.07 | A | G | MKI67IP | 5.53 | 0.01 |
| rs72842201 | 6.13E-06 | 0.07 | A | G | MARCH.10 | 2.99 | 0.05 |
| rs3172278 | 7.23E-06 | 0.07 | T | C | PPP4R2 | 4.04 | 0.49 |
| DOMINANT MODEL | |||||||
| rs3172278 | 2.40E-08 | 1.23E-03 | T | C | PPP4R2 | 0.09 | 0.49 |
| rs2247870 | 1.60E-07 | 4.10E-03 | G | A | GPR98 | 0.4 | 0.47 |
| rs9463 | 3.07E-07 | 5.26E-03 | G | A | TTLL12 | 0.17 | 0.42 |
| rs28656102 | 1.22E-06 | 0.02 | T | C | PPP4R2 | 0.18 | 0.42 |
| rs1045960 | 6.22E-06 | 0.05 | C | T | PPP4R2 | 0.21 | 0.42 |
| rs62039297 | 6.29E-06 | 0.05 | G | A | SRL | 0.2 | 0.26 |
| rs9873229 | 9.72E-06 | 0.07 | C | T | PPP4R2 | 0.22 | 0.44 |
| RECESSIVE MODEL | |||||||
| rs7620924 | 8.07E-11 | 1.08E-05 | A | G | PPP4R2 | 11.77 | 0.49 |
| rs537453728 | 4.53E-08 | 3.04E-03 | CT | C | MAP3K4 | 0.14 | 0.01 |
| rs9310254 | 7.49E-07 | 0.03 | T | C | PPP4R2 | 5.56 | 0.49 |