Table 1.
Patient characteristics.
| Overall (n = 479) | Group 2 LHD (n = 103) | Group 3 Lung (n = 147) | Group 4 CTEPH (n = 202) | Group 5 Unclear (n = 27) | |
|---|---|---|---|---|---|
| Female (n (%)) | 240 (50) | 69 (67) | 51 (35) | 105 (52) | 15 (56) |
| Age (years) | 65 ± 13 | 70 ± 10 | 66 ± 11 | 61 ± 15 | 58 ± 15 |
| WHO FC I + II/III + IV (%) | 17/83 | 28/72 | 12/88 | 15/85 | 15/85 |
| mRAP (mmHg)* | 10.0 (8.0) | 14.0 (9.0) | 9.0 (6.0) | 10.0 (7.0) | 11.0 (10.0) |
| mPAP (mmHg) | 43 ± 11 | 39 ± 13 | 43 ± 12 | 47 ± 11* | 43 ± 12 |
| PWP (mmHg) | 13.8 ± 6.7 | 23.2 ± 4.3 | 11.9 ± 5.0 | 10.6 ± 4.4 | 10.4 ± 4.2 |
| CI (L/min/m2)* | 2.6 (1.1) | 2.9 (0.8) | 2.8 (1.3) | 2.4 (1.0)* | 2.8 (1.5) |
| PVR (Wood Unit)* | 5.8 (6.7) | 2.7 (2.3) | 5.3 (6.0) | 8.4 (6.1)* | 6.0 (6.8) |
| SmvO2 (%) | 62 ± 9 | 64 ± 9 | 65 ± 8 | 60 ± 8* | 59 ± 11 |
| FEV1 (%pred) | 69 ± 23 | 69 ± 21 | 55 ± 24 | 79 ± 18 | 68 ± 25 |
| FVC (%pred) | 83 ± 24 | 78 ± 23 | 74 ± 27 | 91 ± 20 | 81 ± 19 |
| FEV1/FVC (%) | 68 ± 13 | 71 ± 10 | 60 ± 17 | 71 ± 12 | 68 ± 17 |
| Tlco (%pred) | 53 ± 21 | 62 ± 17 | 34 ± 17 | 63 ± 16 | 41 ± 21 |
| ISWT distance (m)* | 120 (160) | 120 (150) | 80 (130) | 140 (210) | 120 (160) |
| ISWT time (min)* | 3.2 (2.9) | 3.2 (2.8) | 2.4 (2.6) | 3.5 (3.4) | 3.2 (2.8) |
Values are presented as mean ± SD for parametric data and *median (IQR) for non-parametric data.
mRAP, mean right atrial pressure; mPAP, mean pulmonary artery pressure; PWP, pulmonary wedge pressure; LHD, left heart disease; CTEPH, chronic thromboembolic pulmonary hypertension; CI, cardiac index; PVR, pulmonary vascular resistance; SmvO2, mixed venous oxygen saturation; FEV1, forced expiratory volume in 1 s; %pred, % predicted; FVC, forced vital capacity; TLco, transfer factor of the lung for carbon monoxide; ISWT, incremental shuttle walk test.