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. 2019 May 29;38:229. doi: 10.1186/s13046-019-1233-9

Fig. 9.

Fig. 9

a-b Expression of phospho-AMPKα (Thr172) in HIG2-silenced HCC cells. c Effect of metformin hydrochloride, an activator of AMPK signaling, on IL-10 expression in HIG2-silenced HCC cells. d Dual luciferase reporter assay was performed to detect the change of transcriptional activity of IL-10, *P < 0.05 compared with the NC group