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Interindividual variation in PC1/3 expression. Photomicrographs illustrate expression of PC1/3 in representative islets of pancreas of 18 donor controls. Islets were double-labeled for insulin (red) and PC1/3 (green). Beta cells with high level of PC1/3 are yellow while cells with lower level of the convertase appear red/orange. Note the variation in enzyme expression between different islets. Bar: 20 µm. Abbreviation: PC1/3, proprotein convertase 1/3.
