Table 1.

Dictionaries used in DES-RedoxVasc with data source references.

Dictionary	Enriched unique terms in the KB	Status
Chemicals/compounds
Chemical Entities of Biological Interest (ChEBI) [84]	17981
Toxins (T3DB) [85]	2083
Lipids (lipids maps) [86, 87]	2852
Amyloids (Human and Mouse); compiled in-house	393	Newly compiled
Functional annotation
Biological Process (GO) [88]	5438
Cellular Component (GO) [88]	1125
Molecular Function (GO) [88]	1755
Pathways (KEGG [89], Reactome [90], UniPathway [91], and PANTHER [92])	1445
Diseases
DOID Ontology (BioPortal)—Human Disease Ontology [93]	3467
ADO Ontology (BioPortal)—Alzheimer's disease ontology [94]	937	Newly compiled
DMTO Ontology (BioPortal)—Diabetes Mellitus Treatment Ontology [95]	1941	Newly compiled
HFO Ontology (BioPortal)—Heart Failure Ontology [96]	1001	Newly compiled
CVDO Ontology (BioPortal)—Cardiovascular Disease Ontology [97]	53	Newly compiled
HP Ontology (BioPortal)—Human Phenotype Ontology [98]	3204
UBERON Ontology (BioPortal)—Uber Anatomy Ontology [99]	6540	Newly compiled
ICD9 Ontology (BioPortal)—International Classification of Diseases, Version 9 - Clinical Modification [100]	688
Drugs
Drugs (DrugBank) [101]	3918
ATC Ontology (BioPortal)—Anatomical Therapeutic Chemical Classification [102]	1991	Newly compiled
CSSO Ontology (BioPortal)—Clinical Signs and Symptoms Ontology	210	Newly compiled
SIDER (Drug Indications and Side Effects) [103]	3190
Human
Human Genes and Proteins (Entrez Gene) [104]	21858
Human Transcription Factors [105]	1505
Human Transcription Co-Factors (TcoF-DB) [105]	384
Human microRNAs (HGNC and Entrez Gene) PMEDIDs for HGNC and Entrez Gene	1811	Updated
Human Long Non-Coding RNAs (HGNC) [106]	460
Mutations (tmVar) [107]	12514
Human Anatomy (in-house compiled)	2538
OMIT Ontology (BioPortal)—Ontology for MicroRNA Target [108]	656	Newly compiled