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. 2019 Mar 11;169(2):567–578. doi: 10.1093/toxsci/kfz070

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© The Author(s) 2019. Published by Oxford University Press on behalf of the Society of Toxicology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Effect of LEV therapy on immobility time in DFP rats. FST: Graph shows increased immobility time in DFP+SAL rats compared with CTL+SAL rats indicating that DFP treatment produced increased behavioral despair. A decreased immobility time in DFP+LEV compared with DFP+SAL rats during the FST, indicated improvement in behavioral despair score. DFP+LEV immobility time was significantly higher than CTL+LEV group suggesting that LEV therapy could not restore despair-like symptoms to baseline values. No significant differences in immobility times were noted between CTL+SAL and CTL+LEV groups (Data expressed as mean ± SEM, *#p < .05, 1-way ANOVA, Tukey’s test, n = 7 rats; *compared with CTL+SAL and #compared with DFP+SAL).