Table 2.

Secondary end points (N = 29)

	Crushed Intranasal IR Oxycodone vs Crushed Intranasal Oxycodone ARIR		Intact Oral Oxycodone ARIR vs Crushed Intranasal Oxycodone ARIR		Crushed Intranasal IR Oxycodone vs Intact Oral Oxycodone ARIR
Secondary End Point	LS Means, mm	P value	LS Means, mm	P value	LS Means, mm	P Value
Overall drug liking	80.78 vs 63.84	<0.0001	78.16 vs 63.84	0.0004	80.78 vs 78.16	NS
Take drug again	82.07 vs 61.83	<0.0001	76.72 vs 61.83	0.0014	82.07 vs 76.72	NS
Drug effects questionnaire
Any effects	64.55 vs 38.26	<0.0001	62.79 vs 38.26	<0.0001	64.55 vs 62.79	NS
Good effects	68.15 vs 39.97	<0.0001	64.06 vs 39.97	<0.0001	68.15 vs 64.06	NS
Drug high	66.10 vs 38.34	<0.0001	65.78 vs 38.34	<0.0001	66.10 vs 65.78	NS
Bad effects	12.73 vs 15.73	NS	13.22 vs 15.73	NS	12.73 vs 13.22	NS
Sick	7.73 vs 6.39	NS	9.49 vs 6.39	NS	7.73 vs 9.49	NS
Nausea	7.36 vs 6.38	NS	4.94 vs 6.38	NS	7.36 vs 4.94	NS
Dizzy	9.78 vs 6.86	NS	10.38 vs 6.86	NS	9.78 vs 10.38	NS

IR = immediate release; LS = least squares; NS = not significant.