Table 2.
ROBINS-I overall risk of judgement for non-randomised intervention studies
| Study | Judgement | Criterion |
| Bonthala (2000)8 | The study has some important problems. | The study is judged to be at serious risk of bias across the confounding and selection of participants domains, but not at critical risk of bias in any domain. |
| Isenberg (1984 March)18 | The study has some important problems. | The study is judged to be at serious risk of bias in classification of intervention domain, but not at critical risk of bias in any domain. |
| Isenberg (1984 July)40 | The study provides sound evidence for a non-randomised study but cannot be considered comparable to a well-performed randomised trial. | The study is judged to be at low or moderate risk of bias for all domains, except for bias due to missing data as there was insufficient information provided. |
| Mirmanesh (1992)22 | The study provides sound evidence for a non-randomised study but cannot be considered comparable to a well-performed randomised trial. | The study is judged to be at low or moderate risk of bias for most domains; however, there was insufficient information to determine bias in deviation from intervention, missing data and outcome measures. |
| Ogut (1996)26 | The study provides sound evidence for a non-randomised study but cannot be considered comparable to a well-performed randomised trial. | The study is judged to be at low or moderate risk of bias for most domains; however, there was insufficient information to determine bias in selection of participants, deviation from intended intervention and missing data. |
| Wheatcroft (1993)1 | The study provides sound evidence for a non-randomised study but cannot be considered comparable to a well-performed randomised trial because there is a significant lack of information in the methods section of the paper. | The study is judged to be at low or moderate risk of bias for most domains; however, there was insufficient information to determine bias in selection of participants, deviation from intended intervention, missing data and the reported results. |