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. 2019 May 9;3(1):e000448. doi: 10.1136/bmjpo-2019-000448

Table 8.

Publications providing data on respiratory adverse effects

Paper Regimen Adverse effect
Alshafei (2017)6 P 2.5%, T 0.5% (3 d) No adverse effect on oxygen saturation, not statistically significant
Jiang (2016)10 P 0.5%, T 0.5% (3 d) Apnoea: statistically significant increase (p<0.05).
Mitchell (2016)28 P 1%, C 0.2% (3 d) Desaturations more likely in oxygen therapy group (p=0.01)
Mirmanesh (1992)22 P 2.5% (3 d) Infants with BPD;

  • Reduction in mean pulmonary compliance (p<0.03)

  • Increased mean total resistance (p<0.01)

  • Reduced expiratory airflow (p<0.03)
Punyawattanporn (2009)41 Not identified Apnoea: one infant.

C, cyclopentolate;P, phenylephrine;T, tropicamide; d, standard drop.