Table II.

Flow mediated dilation in systemic sclerosis patients stratified by presence of digital ulcerations.

Vascular function variables in 70 SSc patients at follow-up FMD	Difference between SSc patients with DU (n=32) and those without DU (n=38)	p value
Baseline flow	−17.2 ± 6.9	0.01
Absolute FMD	−.03 ± .04	0.50
Normalised absolute FMD	0.00007 ± .00006	0.25
Relative FMD	−0.7 ± 1.3	0.58
Normalised relative FMD	−0.002 ± 0.002	0.33
Shear Rate	−5013 ± 3238	0.12
Peak Hyperemia	31.0 ± 36	0.39
Vascular resistance	0.57 ± 0.34	0.09
Change in Baseline flow*	−40.8 ± 12.9	0.002
Normalised Absolute FMD change*	−0.00007	.30
Absolute FMD change*	−0.002 ± 0.05	0.96
Relative FMD change*	−0.3 ± 1.53	0.84
Normalised Relative FMD change*	−0.002 ± .002	0.3
FMD Shear Rate change*	−14374 ± 4037	0.0001
FMD Peak Hyperaemia change*	−33.8 ± 37.7	0.36
Normalised FMD change*	−0.00002 ± 0.00004	0.57

^*Change between measures at baseline FMD adjusted for days between measures and duration of SSc.