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. 2019 May 9;160(6):1506–1514. doi: 10.1210/en.2019-00073

Table 2.

Reg Proteins Binding to Extl3

Reg Protein Signaling Pathway Function
Reg1 Activation of MAPK-JNK-cyclin D1 Pancreatic cell growth
Reg3γ Activation of PI3K-AKT Keratinocyte proliferation and differentiation
Inhibition of TLR3 via AKT-STAT3-SHP1 Promoting wound healing

Abbreviation: JNK, c-Jun N-terminal kinase.