Table 1.
Maternal Serum E2 levels (ng/mL) and Placental, Maternal, and Fetal Body Weights in Baboons
Treatment | N | Saphenous Vein | Uterine Vein | Placental Weight, g | Fetal Weight, g | Maternal Weight, kg |
---|---|---|---|---|---|---|
Untreated | 11 | 0.21 ± 0.03a | 0.59 ± 0.08a | 32.0 ± 1.8 | 12.6 ± 0.5 | 16.5 ± 0.7 |
E2 | 11 | 0.82 ± 0.05b | 1.15 ± 0.05b | 29.0 ± 1.1 | 11.3 ± 0.5 | 15.7 ± 0.5 |
E2 + VEGF | 6 | 0.87 ± 0.07b | 0.98 ± 0.06b | 30.4 ± 2.1 | 13.6 ± 0.9 | 15.8 ± 0.5 |
Mean ± SE maternal saphenous and uterine vein serum E2 levels and placental, maternal, and fetal body weights on day 60 of gestation in baboons untreated or treated daily on days 25 to 59 (term, 184 d) with E2 (25 µg/kg body weight/d SC) or on days 25 to 59 with E2 (25 µg/kg body weight/d) plus VEGF DNA delivered by CEU/MB to PBP on days 25, 35, 45, and 55.
Values marked with different letters are statistically different at P < 0.01.