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. 2019 May 30;15(5):e1006694. doi: 10.1371/journal.pcbi.1006694

Table 1. Physiological parameters of the model presented along with their physiological ranges.

No Physiological parameter Symbol Min Max
1 Mean resting membrane potential of the excitatory population herest -80 mV -60 mV
2 Mean resting membrane potential of the inhibitory population herest -80 mV -60 mV
3 Mean Nernst membrane potential of the excitatory population heeq -20 mV 10 mV
4 Mean Nernst membrane potential of the inhibitory population hieq -20 mV 10 mV
5 Maximum mean firing rate of the excitatory population Semax 0.05/ms 0.5/ms
6 Maximum mean firing rate of the inhibitory population Simax 0.05/ms 0.5/ms
7 Firing thresholds of the excitatory population μe -55 mV -40 mV
8 Firing thresholds of the inhibitory population μi -55 mV -40 mV
9 Std. deviation of firing thresholds of the excitatory population σe 2 mV 7 mV
10 Std. deviation of firing thresholds of the inhibitory population σi 2 mV 7 mV
11 Passive membrane decay time const. of the excitatory population τe 5 ms 150 ms
12 Passive membrane decay time const. of the inhibitory population τi 5 ms 150 ms
13,14 Excitatory postsynaptic potential rate constant γee, γei 0.1/ms 1.0/ms
15,16 Inhibitory postsynaptic potential rate constant γie, γii 0.01/ms 0.5/ms
17 Postsynaptic potential amplitude of the excitatory population Γe 0.1 mV 2.0 mV
18 Postsynaptic potential amplitude of the inhibitory population Γi 0.1 mV 2.0 mV
19 Rate of the excitatory input to the excitatory population pee 0.0 /ms 10.0/ms
20 Rate of the excitatory input to the inhibitory population pei 0.0 /ms 10.0/ms
21 Rate of the inhibitory input to the excitatory population pie 0.0/ms(fixed)
22 Rate of the inhibitory input to the inhibitory population pii 0.0/ms(fixed)
23 Total number of connections an excitatory neuron receives from nearby excitatory neurons Neeβ 2000 5000
24 Total number of connections an inhibitory neuron receives from nearby excitatory neurons Nieβ 100 1000
25 Total number of connections an excitatory neuron receives from nearby inhibitory neurons Neiβ 2000 5000
26 Total number of connections an inhibitory neuron receives from nearby inhibitory neurons Niiβ 100 1000

Among the 26 physiological parameters involved in the model, there are only 22 unknown parameters that are fit to the data (In our implementation, pie and pii are fixed constants, γee = γeiγe, and γie = γiiγi).