Table 1. Physiological parameters of the model presented along with their physiological ranges.
No | Physiological parameter | Symbol | Min | Max |
---|---|---|---|---|
1 | Mean resting membrane potential of the excitatory population | -80 mV | -60 mV | |
2 | Mean resting membrane potential of the inhibitory population | -80 mV | -60 mV | |
3 | Mean Nernst membrane potential of the excitatory population | -20 mV | 10 mV | |
4 | Mean Nernst membrane potential of the inhibitory population | -20 mV | 10 mV | |
5 | Maximum mean firing rate of the excitatory population | 0.05/ms | 0.5/ms | |
6 | Maximum mean firing rate of the inhibitory population | 0.05/ms | 0.5/ms | |
7 | Firing thresholds of the excitatory population | -55 mV | -40 mV | |
8 | Firing thresholds of the inhibitory population | -55 mV | -40 mV | |
9 | Std. deviation of firing thresholds of the excitatory population | σe | 2 mV | 7 mV |
10 | Std. deviation of firing thresholds of the inhibitory population | σi | 2 mV | 7 mV |
11 | Passive membrane decay time const. of the excitatory population | τe | 5 ms | 150 ms |
12 | Passive membrane decay time const. of the inhibitory population | τi | 5 ms | 150 ms |
13,14 | Excitatory postsynaptic potential rate constant | γee, γei | 0.1/ms | 1.0/ms |
15,16 | Inhibitory postsynaptic potential rate constant | γie, γii | 0.01/ms | 0.5/ms |
17 | Postsynaptic potential amplitude of the excitatory population | Γe | 0.1 mV | 2.0 mV |
18 | Postsynaptic potential amplitude of the inhibitory population | Γi | 0.1 mV | 2.0 mV |
19 | Rate of the excitatory input to the excitatory population | pee | 0.0 /ms | 10.0/ms |
20 | Rate of the excitatory input to the inhibitory population | pei | 0.0 /ms | 10.0/ms |
21 | Rate of the inhibitory input to the excitatory population | pie | 0.0/ms(fixed) | |
22 | Rate of the inhibitory input to the inhibitory population | pii | 0.0/ms(fixed) | |
23 | Total number of connections an excitatory neuron receives from nearby excitatory neurons | 2000 | 5000 | |
24 | Total number of connections an inhibitory neuron receives from nearby excitatory neurons | 100 | 1000 | |
25 | Total number of connections an excitatory neuron receives from nearby inhibitory neurons | 2000 | 5000 | |
26 | Total number of connections an inhibitory neuron receives from nearby inhibitory neurons | 100 | 1000 |
Among the 26 physiological parameters involved in the model, there are only 22 unknown parameters that are fit to the data (In our implementation, pie and pii are fixed constants, γee = γei ≡ γe, and γie = γii ≡ γi).