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. 2019 May 30;14(5):e0216950. doi: 10.1371/journal.pone.0216950

Table 4. Interaction between lifestyle behaviors and the CACNA1D rs9810888 polymorphism on MAP.

Lifestyle behaviors Category Genotype N Mean SE b SE p pinteraction
Protein intake (meat/fish/soy beans/egg) <twice/day GT/TT 495 68.9 0.5 2.50 1.29 0.053 0.453
GG 90 71.4 1.2
≥twice/day GT/TT 292 68.5 0.7 0.95 1.62 0.557
GG 61 69.4 1.5
Fruits and vegetables intakea <twice/day GT/TT 583 68.6 0.5 2.64 1.27 0.037 0.132
GG 101 71.2 1.2
≥twice/day GT/TT 206 69.1 0.7 -0.57 1.60 0.724
GG 51 68.6 1.4
Fried chips/cakes/cookies No GT/TT 183 69.6 0.9 1.27 2.00 0.524 0.892
GG 43 70.9 1.8
Yes GT/TT 597 68.5 0.5 1.70 1.20 0.157
GG 107 70.2 1.1
Western food No GT/TT 528 68.9 0.5 1.09 1.23 0.375 0.390
GG 98 70.0 1.1
Yes GT/TT 250 68.4 0.7 3.06 1.83 0.096
GG 51 71.5 1.7
Soft drink No GT/TT 337 68.6 0.6 0.79 1.55 0.610 0.534
GG 58 69.4 1.4
Yes GT/TT 463 68.9 0.5 2.18 1.31 0.098
GG 95 71.0 1.2
Physical activity <1hour/day GT/TT 358 69.8 0.6 1.71 1.54 0.267 0.939
GG 66 71.5 1.4
≥1hour/day GT/TT 429 67.9 0.5 1.86 1.35 0.167
GG 85 69.7 1.2
Screen time <2 hours/day GT/TT 503 68.3 0.5 0.42 1.26 0.738 0.094
GG 95 68.7 1.2
≥2 hours/day GT/TT 292 69.5 0.7 4.08 1.70 0.017
GG 57 73.6 1.6

Note: Adjusted for sex, age, age square and BMI.

a: for fruit and vegetable intake category, <twice/day means either fruits or vegetables intake <twice/day, and ≥twice/day means both fruits and vegetables ≥twice/day.

MAP: mean arterial pressure. BMI: body mass index. SE: standard error. The mean of BP values was adjusted for sex, age, age square and BMI.