. 2019 May 30;14(5):e0217390. doi: 10.1371/journal.pone.0217390

Table 2. Gender analysis in ACTN3 R577X polymorphism with power sports.

	Test of association					Test of heterogeneity				Test of association					Test of heterogeneity				Effect of outlier treatment
	n	OR	95% CI	CID	P^a	Sports Performance	P^b	I² (%)	AM	n	OR	95% CI	CID	P^a	Sports Performance	P^b	I² (%)	AM	Signi-ficance	Hetero-geneity
	PRO									PSO									Signi-ficance	Hetero-geneity
Male
R	20	1.01	0.87–1.18	0.31	0.87	Null	0.08	33	RE	19	1.06	0.94–1.20	0.26	0.31	MP	0.47	0	F	RNS	EH
X	20	0.75	0.61–0.93	0.32	0.008	MC	0.05	38	RE	19	0.79	0.67–0.94	0.27	0.008	MC	0.35	8	F	---	---
RX	20	1.04	0.87–1.25	0.38	0.66	MP	0.0006	58	RE	19	1.14	1.02–1.28	0.26	0.02	MP	0.45	0	F	GS	EH
Female
R	10	1.39	0.93–2.08	1.15	0.11	MP	0.003	63	RE	8	1.58	1.21–2.06	0.85	0.0009	MP	0.11	40	F	GS	RH
X	10	0.98	0.66–1.46	0.80	0.92	Null	0.08	42	RE	9	1.02	0.78–1.31	0.53	0.91	Null	0.10	40	F	RNS	RH
RX	10	0.94	0.77–1.15	0.38	0.54	MC	0.21	25	F	---	---	-------	-----	---	---	---	---	---	---	---

R: common allele; X: variant allele; RX: heterozygous genotype; n: number of studies; OR: odds ratio; CI: confidence interval; CID: confidence interval difference; P^a: P-value for association; P^b: P-value for heterogeneity; I²: measure of inconsistency expressed in %; AM: analysis model; PRO: pre-outlier; PSO: post-outlier; F: fixed-effects; RE: random-effects; MP: more in power; MC: more in control; Null (ORs 0.97–1.03); values and indicator (SP) in bold indicate significant associations indicating effects on SP only (OR > 1.00); the significance and heterogeneity columns were filled when one or both OR values in PRO and/or PSO was MP, otherwise the columns were dashed; GS: gain in significance; RNS: retained non-significance; EH: eliminated heterogeneity; RH: reduced heterogeneity