Table 2. Immunophenotyping of circulating CD4+ T helper cells drained from the tumor microenvironment of non-IBC and IBC patients.
T helper phenotype | % of cells in non-IBC (n = 10) |
% of cells in IBC (n = 4) |
P value |
---|---|---|---|
Th1 (CD4+IFN-γ+) | 29.6 ± 3.9 | 11.38 ± 0.7 | 0.01** |
Th2 (CD4+IL-4+) | 28.29 ± 3.87 | 12.28 ± 1.43 | 0.03* |
Th17 (CD4+IL-17+) | 33.86 ± 5.27 | 26.18 ± 4.64 | 0.43 |
Treg (CD4+Foxp3+) | 16.15 ± 2.84 | 16.71 ± 4.06 | 0.92 |
Values represent mean percentage ± SEM. n = number of patients.
Statistically significance as determined by Student t test expressed as * P ≤ 0.05, ** P ≤ 0.01