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. 2019 May 30;14(5):e0217550. doi: 10.1371/journal.pone.0217550

Table 4. Summary of CD4+ T helper subsets of normal subjects and non-IBC patients upon direct co-culture with control and Sdc-1-silenced SUM-149 cells.

Phenotype Normal (n = 5) P value Non-IBC (n = 5) P value
Control (%) Sdc-1si (%) Control (%) Sdc-1si (%)
Th1 23.8 ± 3.1 22.31 ± 1.6 1.00 21 ± 3.5 20.4 ± 2.4 0.72
Th2 15.54 ± 0.9 12.44 ± 0.7 0.11 14.6 ± 1.5 15.1 ± 3.6 0.98
Th17 25.4 ± 3.9 28.32 ± 2.2 0.24 26.3 ± 4.2 41.1 ± 5.4 0.03*
Treg 22.61 ± 3.21 28.98 ± 2.56 0.04* 25.2 ± 4.5 30.6 ± 4.3 0.02*
Th1/Treg 1.1 ± 0.15 0.78 ± 0.04 0.09 0.87 ± 0.1 0.71 ± 0.08 0.23

Values represent mean percentage ± SEM. n = number of patients.

Statistically significance as determined by Student t test expressed as * P ≤ 0.05