TABLE 1.
First author | Study type | Total number | PerAF | Control group | Treatment group | Risk of bias | Quality of methodologyb |
---|---|---|---|---|---|---|---|
Atienza14 | RCT | 232 | 117 | PVI | Driver (PAF) ± PVI (PerAF) | No serious limitation | High |
Lin9 | RCT | 68 | 68 | PVI + CFAE | PVI then rotor ablation within CFAE regions | No serious limitation | High |
Narayan13 | Quasiexperimental study | 107a | 76 | PVI ± LA roof line, AT/AFL ablation (PerAF) | Driver then PVI (PAF) ± LA roof line, AT/AFL ablation (PerAF) | Serious | Moderate |
Haïssaguerre12 | Case-controlled study | 103 | 103 | PVI | Driver then LA roof + mitral isthmus line if AF persisted then PVI | Serious | Moderate |
Jadidi15 | Case-controlled study | 85 | 85 | PVI | PVI then rotor in low-voltage areas (<0.5 mV) | Serious | Low |
Seitz16 | Case-controlled study | 105 | 81 | PVI | Driver | Serious | Moderate |
Sommer21 | Cross-sectional study | 20 | 20 | N/A | Driver then PVI (PAF) ± LA roof line, AT/AFL ablation (PerAF) | Serious | Low |
AF = atrial fibrillation; AT/AFL = atrial tachycardia/atrial flutter; CFAE = complex fractionated atrial electrogram; LA = left atrium; PAF = paroxysmal atrial fibrillation; PerAF = persistent atrial fibrillation; PVI = pulmonary vein isolation; RCT = randomized controlled trial.
Procedure numbers.
Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines.