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. 2019 May 16;4(10):e125052. doi: 10.1172/jci.insight.125052

Figure 11. scAAV.CNP.Venus.Plp1miRNA-treated Plp1-Tg mice show improved motor functions.

Figure 11

(A) The total moving distance in open field test, (B) the time hanging on a bar in limb hang test, and (C) the number of missteps in 50 steps of gait in limb slip test for P25 Wt+miRneg mice, Tg+miRneg mice, and Tg+Plp1miRNA mice (n = 10 mice per group) are shown. Statistical significance was determined using 1-way ANOVA with Bonferroni’s post hoc test. ***P < 0.001.