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. 2019 May 16;4(10):e125638. doi: 10.1172/jci.insight.125638

Figure 4. AACOCF3 ameliorated aortic osteogenic/chondrogenic signaling during cholecalciferol overload–induced calcification in vivo.

Figure 4

Scatter dot plots (arithmetic mean ± SEM) (n = 5–6; arbitrary units [a.u.]) of Msx2 (A), Cbfa1 (B), and Alpl (C) relative mRNA expression in aortic tissue of mice receiving vehicle (CTR) or high-dosed cholecalciferol (vD), without or with additional treatment with AACOCF3 (AAC). *P < 0.05, **P < 0.01 vs. control mice; †P < 0.05 vs. vD-treated mice (Steel-Dwass method for A and 1-way ANOVA with Games-Howell post-hoc test for B and C).