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OCA treatment alleviates CCl4-induced HSCs activation and liver fibrosis. (A) Serum ALT and AST levels. (B)–(E) Histological analysis of liver sections. H&E staining (B), Masson staining (C), Sirius Red staining (D) and immunohistochemistry of α-SMA (E). (F) Expression profiling of fibrosis-related genes. Results are mean ± SD (n = 5), *P < 0.05, **P < 0.01, ***P < 0.001, #P < 0.05, ##P < 0.01.
