Figure 5.

In vivo performances of the PB hydrogel in a tumor-bearing mouse model. (A) The retention of the DiR-labeled hydrogel and free DiR solution after peritumoral administration (Ex/Em: 740/820 nm); (B) and (C) the thermographs and the corresponding heating curves of the tumor sites after peritumoral administration of the blank hydrogel or PB hydrogel or the PB nanodispersions plus 808 nm irradiation (1 W/cm²), ^*P < 0.05; D) pictures of the tumor tissues after photothermal therapy (1 W/cm², 5 min) over eight sequential days, the red circle represents visibly undetectable tumor sample; (E) statistic graph of the tumor weights, ^*P < 0.05; F) hematoxylin & eosin staining of the tumor tissues.