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. 2018 Dec 26;9(3):575–589. doi: 10.1016/j.apsb.2018.12.009

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© 2019 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — Physicochemical characterizations of nanoparticles. (A) Size distributions of NPs, membrane, and NNPs as determined by DLS. (B) TEM images of NPs, membrane, and NNPs. Scale bars represent 30 nm. (C) Hydrodynamic size of PEG-PLGA NPs cores, membrane vesicles, and NNPs. Data represent mean±SD (n=3). (D) Surface ζ potential of neutrophils, PEG-PLGA NPs cores, membrane vesicles, and NNPs. Data represent means±SD (n=3). (E) Hydrodynamic size of NNPs as measured by DLS at varying membrane protein to PEG-PLGA weight ratios after adjusting to 1× PBS, and after storage for 48 h in 1× PBS. Data represent means±SD (n=3). (F) Comparative proteomic study of plasma membrane proteins of neutrophils and NNPs.