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. 2018 Dec 26;9(3):575–589. doi: 10.1016/j.apsb.2018.12.009

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© 2019 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Cytotoxicity and apoptosis. (A) Viability of Panc02 cells after 24 h of treatment of CLT solution, NPs/CLT and NNPs/CLT. (B) Cell apoptosis and necrosis percentages were analyzed by flow cytometry using annexin V-FITC in combination with PI in Panc02 cells after treatment with different formulations. Data represent mean±SD (n=3). ^&P<0.05 vs. CLT, ^*P<0.05 vs. NPs/CLT.