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. 2019 Jan 24;9(3):505–515. doi: 10.1016/j.apsb.2019.01.010

Figure 7.

Fig. 7

SalA reduced infarct volume, neurological deficit scores, and inhibited neuron and endothelial cells apoptosis in MCAO/R rats. (A) TUNEL and NeuN staining of cortex region. (B) The percent of TUNEL+NeuN positive cells of total neurons in cortex region. (C) TUNEL and NeuN staining of hippocampus region. (D) The percent of TUNEL+NeuN positive cells of total neurons in the hippocampus region. (E) TUNEL and GLUT1 staining of ischemic penumbra region. (F) The percent of TUNEL+GLUT1 positive cells of total GLUT1 positive cells in the ischemic penumbra region. (G) TTC staining of brain slices. (H) Percent of infarct volume calculated according to the thickness of brain slice and the area of infarct region by TTC staining (n=12). (I) Neurological deficit scores (n=18). ###P<0.001 compared with sham group, ***P<0.001 compared with I/R group, ^^P<0.01 and ^^^P<0.001 compared with I/R+SalA group. Scale bar=50 μm.