Figure 3.

Molecular interactions between Rv1087 and cofactors. (a) A strontium ion (purple sphere) is coordinated by Asp-139, Asp-165, Asn-166 (green), two water molecules (red), and Asp-178 of a nearby subunit (yellow), which constitute the pseudobipyramidal metal coordination geometry. Metal-ligand distances averaged over eight subunits are labeled in Å. (b) Average distances of hydrogen bonds between SAH (blue) and amino acid residues (black) less than 3.2 Å in length are shown, where the distances of universally observed interactions in all eight chains are illustrated by red broken lines, and those observed in selective chains are black. The distance between the sulfur atom of SAH and the strontium ion (purple circle) is shown with solid black arrows.