Table 2.
Clinical, biological and angiographic data.
| n (%), median (interquartile range), mean (±standard deviation) | AKI (n = 21) | No AKI (n = 195) | P |
|---|---|---|---|
| Clinical and echocardiographic data | |||
| Acute coronary syndrome | 0.544 | ||
| Unstable angina | 1 (4.8%) | 25 (12.8%) | |
| NSTEMI | 11 (52.4%) | 89 (45.6%) | |
| STEMI | 9 (42.9%) | 81 (41.5%) | |
| Killip stage at admission >1 | 11 (52.4%) | 28 (15.4%) | <0.001 |
| Systolic blood pressure, mmHg | 140.8 (±40.4) | 145.3 (±28.7) | 0.513 |
| Diastolic blood pressure, mmHg | 82.6 (±21.8) | 84.8 (±18.7) | 0.608 |
| LVEF (%) | 48 (±14) | 54 (±10) | 0.043 |
| GRACE Score | 169 (±38) | 127 (±31) | <0.001 |
| Mehran Score | 10.1 (±5.5) | 4.8 (±3.8) | <0.001 |
| Treatment at admission | |||
| Beta-blockers | 6 (28.6%) | 51 (26.2%) | 0.811 |
| RAAS inhibitors | 11 (52.4%) | 64 (32.8%) | 0.074 |
| Diuretics | 3 (14.3%) | 28 (14.4%) | 0.99 |
| Treatment during CCU stay | |||
| Beta-blockers | 15 (71.3%) | 141 (72.4%) | 0.932 |
| RAAS inhibitors | 14 (66.7%) | 150 (76.9%) | 0.296 |
| Diuretics | 9 (42.9%) | 36 (18.5%) | 0.009 |
| Vasopressive drugs | 4 (2%) | 1 (4.7%) | 0.430 |
| Biological data | |||
| Anemia | 7 (33%) | 44 (22%) | 0.284 |
| Troponin peak, μg/L | 75.1 (±96.7) | 41.2 (±70.3) | 0.045 |
| NT-proBNP, pg/mL | 4108.8 (±7021.1) | 1296.6 (±3438.3) | 0.084 |
| log NT-proBNP | 7.4 (±1.6) | 5.7 (±1.7) | <0.001 |
| Creatinine, µmol/L | 107.3 (±52.3) | 78.5 (±20.4) | 0.021 |
| Creatinine on day 2, µmol/L | 147.5 (±76.6) | 83.2 (±18.7) | 0.001 |
| eGFR at admission (CKD-EPI), mL/min/1.73 m². | 67.8 (±27.4) | 87.4 (18.6) | <0.001 |
| eGFR at admission (modified MDRD), mL/min/1.73 m² | 75.1 (±33.4) | 94.1 (±25.3) | 0.018 |
| Angiographic data | |||
| Angioplasty | 16 (76.2%) | 153 (78.5%) | 0.811 |
| Aortocoronary bypass surgery | 3 (14.3%) | 13 (6.7%) | 0.205 |
| IABP | 1 (4.8%) | 0 (0.0%) | 0.002 |
| Injected contrast volume (mL) | 162 (±75) | 146 (±63) | 0.249 |
| Initial SYNTAX score | 14.2 (±9.1) | 11.9 (±9.6) | 0.293 |
AKI: acute kidney injury; CCU: coronary care unit; eGFR: estimated glomerular filtration rate; IABP: intra-aortic balloon pump, LVEF: left ventricular ejection fraction; NSTEMI: acute myocardial infarction without ST segment elevation; NT-proBNP: N terminal pro-brain natriuretic peptide; RAAS: renin-angiotensin-aldosterone system; STEMI: acute myocardial infarction with ST segment elevation.