Figure 3.
Caspase activity measured by the DEVD cleavage test in the striata of immature rats exposed in vivo to Mn for twenty days (PN8-PN-27). The panel shows the DEVD cleavage test from rats treated with saline (control; NaCl 0.9%) or MnCl2 at doses of 5, 10 or 20 mg/kg/day (PN8–27) and the structures analyzed at PN29. Results represent mean ± S.E.M and are expressed as percentage of control (100%). Statistical analysis was performed by ANOVA followed by Duncan’s test. n = 8; *** p < 0.001 compared to control.