Figure 5.

Motor coordination in rats exposed in vivo to Mn. Control and treated rats were tested on 22, 29 and 36 days of age (3, 4 and 5 week-old) on the rotarod task. The graphic shows the overall latency for falling in rats treated (PN8–27) with saline (control; NaCl 0.9%) or MnCl₂ at doses of 5, 10 or 20 mg/kg/day. Results represent median ± interquartile range and are expressed in seconds (s) to latency for falling derived from twelve independent experiments. Statistical analysis was performed by Kruskal-Wallis followed by Dunn’s post-hoc test. * p < 0.05 compared to control.