Figure 9.

Effects of Trolox™ on motor coordination of immature rats exposed to Mn. Rats were treated for twenty days (PN8–27) with saline (control; NaCl 0.9%), MnCl₂ 20 mg/kg (Mn), Trolox™ 1 mg/kg (Tr) or MnCl₂ 20 mg/kg plus Trolox™ 1 mg/kg (Mn + Tr), and tested on 22, 29 and 36 days of age (3, 4 and 5 week old) on the rotarod task. The graphic shows the overall latency for falling and results represent mean ± interquartile range and are expressed as seconds (s) to latency for falling derived from twelve independent experiments. Statistical analysis was performed by Kruskal-Wallis followed by Dunn’s post-hoc test. * p < 0.05 compared to control., # p < 0.05 compared to 20 mg Mn/kg group.