Table 2. Adverse events in patients receiving nivolumab with- and without bevacizumab.

Adverse events		Nivolumab		Comment	Total
		With bevacizumab	Without bevacizumab
No		5	9		14
Grade
	1	NA	NA	Not systematically reported	NA
	2	1	1	Pancytopenia (1) and skin rash (1)	2
	3	1	1	Hepatitis (1) and pneumonitis (1)	2
	4	0	0	NA	0
	5 (death)	1	0	Intestinal perforation causing peritonitis, sepsis and death	1

All adverse events were treated successfully with steroids. Treatment was discontinued for both patients with grade 3 events. The intestinal perforation was believed to be caused by bevacizumab and not nivolumab.

NA, not applicable.