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. 2019 May 24;7:122. doi: 10.3389/fbioe.2019.00122

Table 4.

Comparison of different optimization criteria for different sampling points.

Sampling points A-criterion Q-criterion Q-criterion with FIM based scatter
Good 0.01 0.08 0.07
Intermediate 1 0.08 0.55 0.54
Intermediate 2 0.28 2.09 1.81
Bad 3.35 12.86 22.10

Shown are the A- as well as the Q-criterion compared to the Q-criterion calculated for a multivariate Gaussian distribution with its covariance matrix derived from the FIM.