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. 2019 May 21;23:101866. doi: 10.1016/j.nicl.2019.101866

Table 2.

The global brain volume and cortical surface measurements in CS and NC participants.

CS (N = 10)Mean [SD] NC (N = 20)Mean [SD] The rate of CS/NC p AbsoluteCohen's d
CSF (mm3) 62,785 [29566] 41,841 [11099] 1.5 0.055 1.1
Cortical GM (mm3) 564,306 [166592] 584,210 [87402] 0.97 0.67 0.17
WM (mm3) 419,852 [173140] 482,119 [91980] 0.87 0.21 0.5
Subcortical GM (mm3) 36,365 [11813] 36,798 [6429] 0.99 0.90 0.05
Gyrification Index 3.51 [0.54] 3.71 [0.23] 0.95 0.18 0.54
L gyrification index 2.55 [0.37] 2.74 [0.23] 0.93 0.094 0.67
R gyrification index 2.58 [0.31] 2.76 [0.22] 0.93 0.073 0.72
L cortex surface area (mm2) 95,125 [28475] 103,858 [11515] 0.92 0.37 0.47
R cortex surface area (mm2) 94,594 [27763] 103,962 [11897] 0.91 0.20 0.51
L cortex average thickness (mm) 2.84 [0.31] 2.79 [0.20] 1.02 0.55 0.24
R cortex average thickness (mm) 3.01 [0.24] 2.79 [0.19] 1.08 0.013 1.03
L cortex volume (mm3) 260,146 [87057] 278,140 [37010] 0.94 0.43 0.31
R cortex volume (mm3) 265,105 [75202] 278,528 [38143] 0.95 0.52 0.25

Bold indicates statistically significant. Abbreviation; CS, CHARGE syndrome; NC, Normal control; SD, standard deviation; L, left hemisphere; R, right hemisphere; GM, gray matter; WM, white matter; CSF, cerebrospinal fluid.