TABLE 4.
Differentially abundant taxa in vitamin A–supplemented group compared with placebo during early infancy and at 2 y of age in male infants with birth weight below median1
| Log2 fold change (SE) | P | Adjusted P | |
|---|---|---|---|
| Early infancy | |||
| Phylum | |||
| Firmicutes | −0.261 (0.23) | 0.26 | 0.96 |
| Family | |||
| Gemellaceae | −0.646 (0.293) | 0.037 | 0.86 |
| Genus | |||
| Catenibacterium | 0.714 (0.378) | 0.062 | 0.81 |
| 2 y | |||
| Phylum | |||
| Bacteroidetes | 0.485 (0.462) | 0.29 | 0.83 |
| Family | |||
| Porphyromonadaceae | −1.45 (0.466) | 0.0031 | 0.095 |
| Bacteroidaceae | −1.56 (0.644) | 0.017 | 0.25 |
| Eubacteriaceae | −0.6 (0.245) | 0.025 | 0.25 |
| Genus | |||
| Parabacteroides | −1.47 (0.458) | 0.0023 | 0.14 |
| Bacteroides | −1.57 (0.655) | 0.019 | 0.43 |
| Anaerostipes | −0.467 (0.193) | 0.026 | 0.43 |
| Faecalibacterium | 1.16 (0.543) | 0.035 | 0.43 |
1Differential taxa abundance at phylum, family, and genus levels was determined by fitZIG mixture modeling during early infancy (average of 6, 11, and 15 wk; n = 66) and at 2 y of age (n = 57). Taxa with a P value <0.05 or the lowest one were selected for this table. Early-infancy microbiota data were adjusted for type of delivery and breastfeeding status. Microbiota data at 2 y were additionally adjusted for age group at 2 y (older and younger). False discovery rate–adjusted P value (adjusted P) was calculated by the Benjamin-Hochberg method.