TABLE 5.
Differentially abundant taxa in vitamin A–supplemented group compared with placebo during early infancy and at 2 y of age in female infants with birth weight above median1
| Log2 fold change (SE) | P | Adjusted P | |
|---|---|---|---|
| Early infancy | |||
| Phylum | |||
| Fusobacteria | 0.355 (0.27) | 0.20 | 0.77 |
| Family | |||
| Corynebacteriaceae | 0.721 (0.357) | 0.046 | 0.98 |
| Genus | |||
| Corynebacterium | 0.708 (0.361) | 0.052 | 0.96 |
| 2 y | |||
| Phylum | |||
| Actinobacteria | 9.55 (0.316) | 0.049 | 0.15 |
| Bacteroidetes | 4.88 (0.336) | 0.050 | 0.15 |
| Family | |||
| Carnobacteriaceae | −0.381 (0.232) | 0.038 | 0.92 |
| Genus | |||
| Megasphaera | 2.33 (0.639) | <0.001 | 0.031 |
| Faecalibacterium | −1.31 (0.558) | 0.020 | 0.56 |
| Slackia | −0.63 (0.294) | 0.038 | 0.56 |
| Granulicatella | −0.511 (0.233) | 0.038 | 0.56 |
1Differential taxa abundance at phylum, family, and genus levels was determined by fitZIG mixture modeling during early infancy (average of 6, 11, and 15 wk; n = 67) and at 2 y of age (n = 64). Taxa with a P value <0.05 or the lowest one were selected for this table. Early-infancy microbiota data were adjusted for type of delivery and breastfeeding status. Microbiota data at 2 y were additionally adjusted for age group at 2 y (older and younger). False discovery rate–adjusted P value (adjusted P) was calculated by the Benjamin-Hochberg method.