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. 2019 Apr 22;149(6):1075–1088. doi: 10.1093/jn/nxz034

TABLE 8.

Differentially abundant taxa for every unit increase of plasma retinol during early infancy and at 2 y of age in female subjects1

Log2 fold difference (SE) P Adjusted P
Plasma retinol at early infancy
 Microbiota in early infancy
  Phylum
   Proteobacteria −3.75 (2.09) 0.07 0.40
  Family
   Prevotellaceae −7.51 (3.07) 0.015 0.37
   Coriobacteriaceae −9.33 (4.17) 0.026 0.37
   Lactobacillaceae −7.24 (3.65) 0.048 0.46
  Genus
   Prevotella −8.2 (2.99) 0.0065 0.29
   Lactobacillus −7.81 (3.7) 0.035 0.59
   Collinsella −9.26 (4.53) 0.041 0.59
 Microbiota at 2 y
  Phylum
   Verrucomicrobia −1.69 (2.61) 0.52 0.86
  Family
   Comamonadaceae 2.95 (0.898) 0.0030 0.089
   Alcaligenaceae 4.20 (2.09) 0.046 0.72
  Genus
   Acidaminococcus 2.45 (0.588) <0.001 0.023
   Comamonas 2.92 (0.896) 0.0027 0.079
   Mitsuokella −5.89 (2.04) 0.0051 0.101
   Eggerthella 4.55 (1.64) 0.0069 0.101
   Sutterella 4.68 (2.05) 0.024 0.28
   Oscillospira 3.63 (1.80) 0.046 0.45
Plasma retinol at 2 y
 Microbiota at 2 y
  Phylum
   Verrucomicrobia 4.26 (1.10) <0.001 0.0011
   Actinobacteria 1.85 (0.875) 0.036 0.11
  Family
   Verrucomicrobiaceae 4.22 (1.08) <0.001 0.0061
   Turicibacteraceae 3.06 (1.09) 0.0058 0.091
   Carnobacteriaceae −1.74 (0.64) 0.0097 0.101
   Bifidobacteriaceae 1.94 (0.92) 0.037 0.29
  Genus
   Akkermansia 4.29 (1.10) <0.001 0.011
   Turicibacter 3.325 (1.06) 0.0023 0.067
   Eggerthella 2.14 (0.75) 0.0054 0.11
   Granulicatella −1.74 (0.645) 0.0096 0.14
   Slackia −1.65 (0.73) 0.027 0.32
   Actinobacillus −1.55 (0.748) 0.043 0.42

1Differential taxa abundance at phylum, family, and genus levels was determined by fitZIG mixture modeling during early infancy (average of 6, 11, and 15 wk; n = 133) and at 2 y of age (n = 127). Taxa with a P value <0.05 or the lowest one were selected for this table. Plasma retinol concentration is the mean of the 6- and 15-wk values. Early-infancy microbiota data were adjusted for type of delivery and breastfeeding status. Microbiota data 2 y were additionally adjusted for age group at 2 y (older and younger). False discovery rate–adjusted P value (adjusted P) was calculated by the Benjamin-Hochberg method.