Table 8.
Genetic model analysis of rs2227473 in the intestinal tuberculosis population
| Genetic model | Genotype | HCs (n) | ITB (n) | OR (95%CI) | P-value | OR (95%CI)1 | P-value1 |
| Dominant | GG | 373 | 112 | 1.00 | 1.00 | ||
| GA + AA | 127 | 21 | 0.58 (0.35-0.96) | 0.034 | 0.58 (0.34-0.98) | 0.040 | |
| Recessive | GA + GG | 483 | 131 | 1.00 | 1.00 | ||
| AA | 17 | 2 | 0.43 (0.10-1.90) | 0.268 | 0.45 (0.10-1.99) | 0.291 | |
| Co-dominant | GG | 373 | 112 | 1.00 | 1.00 | ||
| AA | 17 | 2 | 0.40 (0.09-1.74) | 0.219 | 0.50 (0.11-2.33) | 0.379 | |
| GG | 373 | 112 | 1.00 | 1.00 | |||
| GA | 110 | 19 | 0.61 (0.36-1.03) | 0.064 | 0.63 (0.37-1.08) | 0.091 |
HCs: Healthy controls; ITB: Intestinal tuberculosis; OR: Odds ratio; CI: Confidence interval.
1
Adjusted for gender, age, smoking and drinking history.
Bold indicates the statistical significance (P < 0.05).