Table 9.
Genetic model analysis of rs1143627 in the intestinal tuberculosis population
| Genetic model | Genotype | HCs (n) | ITB (n) | OR (95%CI) | P-value | OR (95%CI)1 | P-value1 |
| Dominant | CC | 137 | 22 | 1.00 | 1.00 | ||
| CT + TT | 363 | 111 | 1.90 (1.16-3.13) | 0.011 | 1.93 (1.14-3.25) | 0.014 | |
| Recessive | CT + CC | 377 | 91 | 1.00 | 1.00 | ||
| TT | 123 | 42 | 1.42 (0.93-2.15) | 0.104 | 1.41 (0.92-2.18) | 0.118 | |
| Co-dominant | CC | 137 | 22 | 1.00 | 1.00 | ||
| TT | 123 | 42 | 2.13 (1.20-3.76) | 0.010 | 3.46 (1.73-6.91) | 0.000 | |
| CC | 137 | 22 | 1.00 | 1.00 | |||
| CT | 240 | 69 | 1.79 (1.06-3.02) | 0.029 | 2.14 (1.22-3.77) | 0.008 |
HCs: Healthy controls; ITB: Intestinal tuberculosis; OR: Odds ratio; CI: Confidence interval.
1
Adjusted for gender, age, smoking and drinking history. Bold indicates the statistical significance (P < 0.05).