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Serum antibody levels following vaccination of pigs with vaccine candidates. M. hyopneumoniae-specific IgG antibodies induced by the five novel vaccines and one commercial vaccine listed in the legend were determined by indirect ELISA. Six animals per group received two injections in 14 days interval. Individual animals are shown. Significance was calculated using two-way ANOVA followed by Tukey's test (*P < 0.05; ,**P < 0.01; ***P < 0.001).
