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. 2019 May 24;10:1087. doi: 10.3389/fimmu.2019.01087

Figure 3.

Figure 3

Innate immune response BTM correlating with adaptive immune responses. Time-dependent changes in scores for BTM were determined using ssGSEA and then correlated to antibodies, M. hyopneumoniae-specific INFγ+TNF+ CD4 T cells and CD8 T cells. Pearson correlation coefficients for the BTM changes from D0 to D1 (D0 vs. D1), from D0 to D7 (D0 vs. D7), and from D1 to D7 (D1 vs. D7) are shown as heat maps. A P < 0.05 was used as cut-off. Red colors indicate positive and blue negative correlations. The BTM were grouped into inflammatory, myeloid cell, DC/antigen presentation and IFN type I BTM as previously described (34). BTM, blood transcriptional modules.