Table 3.
Patient outcome measures in those reporting versus not reporting symptoms in semistructured interviews
| Interviews | Patient Outcome Measure Scores* |
P Value‡ | |||
|---|---|---|---|---|---|
| Qualitative Symptoms Present,†n/N (%) | Overall | Qualitative Symptoms Present | Qualitative Symptoms Absent | ||
| Physical outcomes | |||||
| SF-36 Physical Component Summary | 29/40 (73) | 35 (27–48) | 33 (26–38) | 52 (35–56) | 0.002 |
| EQ-5D Mobility | 30/41 (73) | 2 (1–2) | 2 (1–2) | 1 (1–2) | 0.01 |
| Mental health outcomes | |||||
| HADS Anxiety score | 23/47 (49) | 5 (2–10) | 8 (4–15) | 4 (2–7) | 0.002 |
| Substantial symptoms (score ≥ 8) n (%) | 16 (34) | 13 (57) | 3 (13) | 0.002 | |
| HADS Depression score | 23/34 (68) | 9 (2–11) | 10 (5–12) | 2 (1–9) | 0.01 |
| Substantial symptoms (score ≥ 8) n (%) | 19 (56) | 15 (65) | 4 (36) | 0.15 | |
| IES-R total score | 17/43 (40) | 0.5 (0.1–1.7) | 1.6 (0.2–2.4) | 0.4 (0.0–0.7) | 0.02 |
| Substantial symptoms (score ≥ 1.6) n (%) | 11 (26) | 8 (47) | 3 (12) | 0.01 | |
| Cognitive outcomes | |||||
| Immediate memory: Logical Memory I age-adjusted score | 29/43 (67) | 8 (5–12) | 8 (5–12) | 8 (7–11) | 0.69 |
| Delayed memory: Logical Memory II, age-adjusted score | 27/41 (66) | 8 (6–10) | 8 (4–10) | 8 (6–11) | 0.47 |
| Attention/working memory: Digit Span, age-adjusted score | 29/43 (67) | 9 (7–11) | 9 (7–10) | 10 (6–12) | 0.59 |
Definition of abbreviations: EQ-5D = EuroQol 5 Dimensions; HADS = Hospital Anxiety and Depression Scale; IES-R = Impact of Event Scale - Revised; SF-36 = Short-Form 36 version 2.
Patient outcome measure scoring: SF-36 Physical component summary: normalized scores (mean, 50; standard deviation, 10; higher score is better), EQ-5D-3L: range, 1–3; 1 = no problems in walking about, to 3 = confined to bed. HADS Anxiety and HADS Depression: range, 0–21; lower score is better. IES-R: range, 0–4; lower score is better. Immediate Memory, delayed memory, and working memory: range, 1–19; higher is better.
Scores reported as median (interquartile range) unless otherwise noted.
N is total number of individuals referencing stated topic during interview and a completed patient outcome measure.
P value from Wilcoxon rank sum test for the continuous scores, and Fisher exact test for the comparison of proportion.