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. 2019 Mar 27;133(22):2413–2426. doi: 10.1182/blood.2018872218

Figure 6.

Figure 6.

Partial rescue of Trib1-deficient eosinophil mobilization in response to type 2 lung inflammation. Mice were treated for 5 days with intranasal PBS or 30 μg of papain. (A) Representative plots of lung leukocytes gated on live, CD45+CD11bhiCD11c−. Frequency of live cells (B) and absolute number (C) of lung eosinophils gated on live, CD45+CD11bhiCD11c−SiglecF+ cells. (D) Representative histogram of Ly6G expression by lung eosinophils gated live, CD45+CD11bhiCD11c−SiglecF+, Trib1+/+ (blue), Trib1ΔEos (red). (E) Fraction of lung eosinophils expressing Ly6G; n = 3 mice per group, representative of 2 experiments. Frequencies and error bars are mean ± SEM of live cells.