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. Author manuscript; available in PMC: 2019 Sep 10.
Published in final edited form as: Curr Rheumatol Rep. 2018 Sep 10;20(11):68. doi: 10.1007/s11926-018-0777-6

Table 2.

MSIS definition for PJI and threshold values for minor criteria [58]

Periprosthetic joint infection is defined as:
Major criteria Two periprosthetic cultures with identical organisms
or
A sinus tract communicating with the joint
or
Minor criteria Three of the following five minor criteria
- Elevated CRP and ESR
- Elevated synovial WBC count or positive luekocyte esteraste test trip (synovial fluid)
- Elevated synovial fluid PMN%
- Positive histological analysis of periprosthetic tissue
- A single positive culture
Threshold values Acute PJI (< 6 weeks from surgery): CRP > 100 mg/L, ESR not useful, synovial WBC > 10 k cells/uL, PMN% > 90%
Chronic PJI (> 6 weeks from surgery): CRP >10 mg/L, ESR > 30 mm/h, synovial WBC > 3 k cells per uL, PMN% > 80%