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LPS induced chronic neuroinflammation in rats. Adult male SD rats were given injections of saline, LPS 2.5, 5, and 7.5 mg/kg, ip, and 3 months later, the brains were collected for double stain for dopaminergic neurons (TH-strain, red) and microglia (Iba1-stain, green) (A), and their quantitative cell counts were expressed as % of Controls as described previously (Liu et al. 2008) (B). Values are the mean ± SEM (n = 3).
*Significantly different from the control group, p < 0.05.
